Polynucleotides
Cellular Regeneration. Naturally Healthier Skin.
Polynucleotides represent one of the most exciting advances in regenerative aesthetic medicine. Rather than adding volume or simply masking the visible signs of ageing, they work at a cellular level to stimulate the skin’s natural repair mechanisms, encouraging regeneration from within.
By supporting fibroblast activity and improving the extracellular environment, polynucleotides promote the production of collagen and elastin while enhancing tissue repair, hydration and skin resilience. The result is not a dramatic alteration in your appearance, but healthier, stronger skin with improved texture, elasticity and luminosity.
How It Works
Polynucleotides are highly purified DNA fragments derived from natural biological sources. Once injected into the skin, they provide a regenerative stimulus that encourages fibroblast activity, supports cellular repair and promotes the synthesis of new collagen and elastin. They also help improve hydration, reduce oxidative stress and optimise the extracellular matrix, creating healthier conditions for long-term skin renewal.
As the tissues regenerate over the weeks following treatment, skin quality progressively improves. Fine lines soften, elasticity increases and the skin becomes firmer, smoother and more resilient. Because the treatment works by restoring normal biological function rather than creating artificial volume, results develop gradually and appear entirely natural.
A course of treatment is typically recommended to achieve optimal regeneration, with improvements continuing for several months as collagen remodelling takes place.
Treatment Areas
Polynucleotides can rejuvenate multiple areas, including:
Face
Improves texture, elasticity, and hydration while addressing fine lines, loss of firmness, dullness, uneven tone, and mild scarring.
Neck & Décolletage
Revitalises crepey or sagging skin by encouraging collagen production, leaving the neck firmer, smoother, and more rejuvenated.
Eyes
Reduces dark circles, fine lines, and thinning skin by stimulating collagen and elastin, restoring brightness and a more rested look.
Scalp for Hair Loss
(to support hair follicle
regeneration and hair loss concerns)
Full Face
Neck & Décolletage
Eyes
(ideal if unsuitable for
tear trough filler)
Scalp for Hair Loss
(to support hair follicle
regeneration and hair loss concerns)
Benefits You Can Expect
Stimulates new collagen and elastin production
Deep skin hydration and improved texture
Reduction in fine lines and crepiness
Improved skin elasticity and bounce
Lifts and tightens areas of laxity
Brightens and revitalises overall complexion
Suitable for face, neck, and delicate eye area
Treatment Overview
Expected Results
Progressive improvement in skin quality, hydration, and firmness across the treatment course
Procedure Time
15 minutes
Anaesthesia
Topical numbing cream available; discomfort level low
Downtime
Minimal — occasional mild redness or swelling
Longevity
6–9 months; repeat course recommended every 6–9 months
Sessions Required
3 sessions, 2 weeks apart
FAQs
Who is suitable for polynucleotides?
Can polynucleotides be combined with other treatments?
Yes, they are frequently combined with dermal fillers or anti-wrinkle in the same appointment.
How often can I have polynucleotides?
The standard schedule is three sessions two weeks apart, repeated every six to nine months. Some patients benefit from more frequent maintenance — every three months — which is equally safe.
What aftercare advice should I follow?
After polynucleotide treatments, there are certain post treatment instruction to follow. You will be advised to avoid sun exposure, extreme temperatures, and strenuous activities for a few days. Adhering to the prescribed skincare routine, including SPF, moisturising and gentle cleansing, accelerates healing. Regular follow-up appointments ensure optimal results and ongoing skin health. A comprehensive list of post treatment instructions will be provided at your appointment to ensure you enjoy your results safely.
Ready to rejuvenate your skin from within?
Contact us today to arrange your polynucleotides consultation with Dr Shabri.